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Bluetooth: The future of instant scientific know-how? | 090-601 Study Guide and Practice Test

at the beginning published MDDI February 2002


a new know-how that borrows from telemetry, IrDA, and 802.11 is decided to proceed the wireless vogue.

William E. Saltzstein

scientific equipment designers now have a few wireless alternate options for their items. No single instant technology meets all design goals and addresses all of the concerns introduced to designers. For each design project that contains wireless expertise, choices have to be made to determine most the acceptable technologies for that software and machine-use model. for a lot of purposes, Bluetooth instant technology should be the most applicable alternative.

Bluetooth, while it's in no way the generic solution to all instant wants, addresses lots of the performance requirements particular to clinical applications, and it's a particularly first rate slot in use models disturbing high mobility, lengthy battery lifestyles, and no infrastructure aid. Bluetooth does greater than conveniently dispose of cables; it provides entry to a big range of normal contraptions and communications alternatives, together with the formation of small networks. Bluetooth permits extra communications links by using proposing entry to huge-enviornment networking through cellular telephone statistics communications as well as average Ethernet local-area networks.

the commercial, Scientific, and clinical (ISM) radio-frequency (RF) band within which Bluetooth operates is shared through a number of instant technologies. scientific instruments need to undergo immunity testing for compatibility with other ISM instruments. as a result of Bluetooth uses the lowest transmit energy of the instant technologies, it has the lowest chance of interference. Many companies have examined coexistence issues amongst ISM technologies and concluded that there is little cause for concern in precise use.


Bluetooth is probably the most exact in a string of purchasable wireless technologies. IrDA (overseen via the Infrared machine affiliation), telemetry, 802.11, and residential RF all preceded it. each know-how has its personal particular advantages and disadvantages, and Bluetooth borrows from every of them.

Bluetooth originated as a cable substitute expertise primarily centered at personal, transportable computing and communications equipment, reminiscent of own digital assistants, cell phones, and laptop computer systems. The expertise makes possible not most effective substitute of simple factor-to-factor cabling (with minimal affect in charge and power), but additionally the short and simple advent of small advert hoc networks of devices, or piconets.

The Bluetooth specification turned into created jointly by using Ericsson, IBM, Intel, Nokia, and Toshiba and was named after the tenth- century Danish Viking king Harald "Bluetooth" Blatand, who united the warring factions of Denmark and Norway. a primary purpose of the Bluetooth specification is to create a truly overseas normal to be applied identically global. to this point, this purpose is being met.

nowadays, Bluetooth expertise has a following of greater than 2500 businesses. The initial founders have been joined by way of such companies as 3COM, Lucent, Microsoft, and Motorola. items incorporating Bluetooth wireless expertise at the moment are delivery from many businesses. last year, the Institute of Electrical and Electronics Engineers (IEEE) adopted Bluetooth as the foundation for its own-area community (PAN) regular 802.15.

THE RADIO know-how

As unique by way of Bluetooth, the basic radio to be used transmits 10 m in open air (although existing implementations operate smartly at drastically more desirable latitude), with an optional energy level to permit a hundred-m operation. With a complete bandwidth of 1 Mb/sec, the radio is designed for moderate velocity and a theoretical 720 Kb/sec payload, dividing up the bandwidth among the many instruments the use of facts and voice channels. The know-how supports eight devices on a piconet.

The Bluetooth radio was designed for immunity to noise and for ease of implementation on silicon, with primary baseband parts carried out in either hardware or firmware to optimize charge, vigor, and size. Implementations that contain the whole radio-frequency and baseband processing area on a single chip—and have few external accessories—are already delivery.

To achieve amazing connections, Bluetooth employs three key strategies: frequency hopping, adaptive energy manage, and the transmission of brief data packets. The Bluetooth protocol (for statistics) immediately retransmits corrupt information packets which have—because the pseudorandom hopping sequence is designed to maximize frequency spacing between sequential channel hops—most likely hopped far from the interfering source.

Like other ISM radio technologies, Bluetooth operates in the 2.4–2.485-GHz radio band. Its radio meets the power and spectral emissions requirements defined with the aid of ETSI ETS 300–328 in Europe and FCC below CFR forty seven part 15 in the united states using the following set of parameters:

  • Frequency hopping, unfold spectrum 79 channels, 1600 hops per 2nd.
  • Gaussian frequency shift keying modulation with a 1-m image-per-2d cost or 1 Mb/sec data price.
  • 83.5 MHz of spectrum divided into 1-MHz channels.
  • image timing accuracy ±20 ppm timing (when synchronized).
  • vigor handle in response to bought signal strength intensity feedback from the receiving device (type 1 requirement).
  • 0 dBm (1 mW) without power manage (category 3, 10-m range).
  • 20 dBm (one hundred-mW) with vigour handle (category 1, a hundred-m latitude).
  • Bit error fee of 0.1%, receiver sensitivity of –70 dBm.

    Interfaces turn up in Bluetooth at several diverse stages (see figure 1). Blue RF is an interface designed to allow reuse and interoperability of the Bluetooth radios. besides the fact that children not formally part of the Bluetooth common, it has been adopted through lots of the silicon suppliers as the digital interface to the radio subsystem.

    Baseband processing is responsible for channel coding, decoding, and low-stage timing handle and administration of the link for single statistics-packet transfers. It decodes and encodes packets of records and gives the "care and feeding" of the RF transceiver sections.

    The hyperlink manager is responsible for managing the hyperlink manage states used to set up and hold the connection between the grasp machine and its slaves, and it contains:

  • Inquiry/inquiry scan (used to find different devices; the baseband a part of carrier discovery).
  • page/web page scan (used to set up connections to a chosen equipment).
  • Connections: the active states and the energy-saving states of hold, sniff, and park.
  • The host handle interface (HCI) is a hardware and application interface particular to enable modular implementations of the decrease-level hardware and baseband. Architecturally, HCI permits the burden of the protocol stack to be borne via the host equipment or desktop to reduce total implementation charge. Its hardware interface is specific as both USB or UART. (the use of USB always achieves the highest data costs.)

    The low-degree protocol is answerable for packetization, multiplexing, and demultiplexing packets for the better-degree protocols, and it maintains order within the piconet; this interface is just about Bluetooth's "traffic cop."

    higher-stage Protocols. higher-degree protocols comparable to RFCOMM and service discovery protocol (SDP) provide high-degree functionality upon which profiles are constructed. RFCOMM emulates full "hand-shaking" serial ports and is used in profiles that guide fundamental connections between pairs of contraptions. SDP is described later in this article.

    Transmission Channels. Two kinds of transmission channels are described in Bluetooth: asynchronous communications hyperlink (ACL) and synchronous connection oriented (SCO). ACL channels are used for records communications and are deploy between each two Bluetooth contraptions for use in connection administration. ACL is a packet-switched transmission method that offers error detection, forward error correction, packet monitoring (numbering), and packet retransmission. It gives thoroughly error-free links to the software; they will either provide good records or preserve making an attempt until signaling that the link is broken. (The retransmission of information in the presence of interference increases latency and slows down web records prices.)

    Used for the transmission of voice facts, SCO is a circuit-switched transmission system that provides customary latency and warranted transmission fees, and it points error detection and forward error correction. every SCO channel is given time slots which are predetermined in the transmission sequence, with a highest of three SCO channels accredited in each and every piconet. Little bandwidth is left for ACL statistics when all three SCO channels are being used.

    SCO and ACL channels permit option of each packet length and the quantity of ahead error correction. These parameters are sometimes immediately managed and rely on the volume of interference immunity and data throughput wants.

    Piconets and Scatternets. A Bluetooth piconet incorporates at the least a grasp and a slave; this pairing is defined as some extent-to-aspect connection. A full piconet consists of one master and up to seven slaves. The master controls all timing including the clock and hopping sequence (to which all slaves synchronize). each and every master may have just a little different clock (skew) and hopping sequences, which might be according to the master's equipment tackle (a forty eight-bit IEEE handle). These alterations allow for assorted piconets to be centered and used within the equal real house. A Bluetooth master is liable for controlling all information site visitors in a piconet. All facts transmission goes through the grasp in a celebrity community topology.

    The Bluetooth specification defines the means to change the master and slave relationship between two gadgets: a beautiful function for implementation of LAN access facets. It also permits a tool to be each a master on one piconet and a slave on an extra, or to be a slave on a couple of piconet if the hardware and baseband implementations guide it.

    A scatternet is formed from two or more piconets that share a standard member. This shared member may additionally both be a slave on both piconets, or a grasp on one and a slave on an additional. each of these configurations has architectural exchange-offs, and the current Bluetooth specification (1.1) does not outline the favored one, nor does it fully define the operation of scatternets.

    Profiles. Collections of elements and services required to function a specific operation are called profiles. The simple, required profile gives all contraptions some stage of interoperability—the means to characteristic automatically with different gadgets with little user intervention. This assortment of features is known as the general entry Profile.

    further, not obligatory profiles depend upon the application requirements and implementation particulars. under is an inventory of the profiles presently particular. below development or within the unlock process are profiles for printing, fingers-free, and audiovisual purposes; human interfaces; and others. The version 1.1 profiles are

  • typical access—implemented in all instruments.
  • service Discovery—makes it possible for contraptions to assess capabilities of alternative contraptions.
  • Cordless Telephony—covers functions for cordless mobilephone handsets, both audio and dialing.
  • Intercom—makes it possible for voice connections and calling between two contraptions.
  • Serial Port—includes the features and methods required for establishing a virtual serial connection between two gadgets; it's used in lots of of the better-level profiles.
  • Headset—units forth the features needed to enforce a fingers-free headset for cell phones and computers.
  • Dial-Up Networking—covers the features and methods required to set up a faraway web connection.
  • FAX—specifies instant ship and receive indicators for faxing.
  • LAN access—enables Bluetooth to be used as the transport to a typical native-area community (LAN).
  • widely wide-spread Object change (OBEX)—specifies a way to transmit high-degree objects, similar to information. The basis for here three profiles, OBEX become developed for IrDA and allows for Bluetooth for use via utility functions developed for IrDA.
  • Object Push (OBEX based)—transmits named objects containing statistics.
  • File switch (OBEX primarily based)—transfers info between gadgets.
  • Synchronization (OBEX primarily based)—synchronizes functions on computers, very own digital assistants, and cell phones.
  • KEY BLUETOOTH features

    Bluetooth has been designed to facilitate setup of small agencies of contraptions. Two key features, provider discovery and ad hoc community support, additionally play major roles within the design, and safety points protect the privacy of communications.

    carrier Discovery Protocol. provider discovery protocol (SDP) points enable for automatic awareness and configuration between two contraptions of different types and from distinctive manufacturers.

    There are two forms of discovery inside the Bluetooth specification. machine discovery allows one machine to query instruments inside latitude and purchase, in turn, key information about their regular capabilities. This key information includes full address, human-readable name, and accepted machine classification (cellular telephone, computing device personal computer, headset).

    provider discovery permits a device to be trained the particulars of supported profiles and to in fact browse those profiles to learn the way to entry definite facets. The service discovery idea permits for even more guidance and entry be exchanged.

    ad Hoc Networks. ad hoc networking is the skill to quickly set up and dissolve small businesses of devices with very little person involvement and no permanent address task. a few instruments establish one community and preserve the relationship handiest for the desired time of interplay. If protection is preferred, clients can classification in passwords or personal identification numbers (PINs) for bonding and encryption.

    security. Bluetooth supports a few security facets, reckoning on the application and person requirements. These features latitude from the protection in opposition t eavesdropping inherent to the frequency-hopping unfold-spectrum expertise, to using keys or PIN and password combinations. With the use of PINs (alphanumeric strings of up to sixteen characters), the 128-bit SAFER+ encryption algorithm is used to create very amazing security and encryption between contraptions. greater security can be introduced on the application degree if preferred. This implementation may still meet the necessities of methods that have to conform to the medical insurance Portability and Accountability Act of 1996 privateness requirements.

    BLUETOOTH'S medical functions

    Bluetooth expertise opens up many chances for scientific instruments to talk and facilitate healthcare suppliers' access to primary advice. several stories are being carried out, lots of them in Europe, to evaluate the know-how as a way for synchronizing very own instruments and transferring statistics in hospitals. at least one clinical machine has been listed on the Bluetooth net site as a Bluetooth-accepted product. other instruments developed by way of two groups have been proven, and are serving as feasibility prototypes for Bluetooth implementation. These consist of a affected person-worn pulse oximeter and a conveyable patient video display.

    scientific assistance. Use of handheld and cellular computing expertise in the scientific container has improved incessantly. medical doctors automatically access medical databases for drug dosages and interactions. home-fitness nurses keep suggestions on their sufferers for container use. Many other functions are enabling practitioners to make improved-informed choices.

    Bluetooth wireless technology will permit scientific gadgets to connect more without problems with each and every other and to advice access elements supplied by LANs. Bluetooth's low vigor, within your means, and few configuration requirements may be traded off towards 802.11b's bigger speed and straightforward business integration. The use mannequin and ambiance for each and every particular person software will examine the best choice for wireless information know-how.

    clinical gadgets. other wonderful percentages exist in the container of scientific device communications and networking. Bluetooth evidently gives an competencies for enormously cellular battery-powered gadgets, and it opens up the chance for these devices to connect with a LAN or extensive-area network. enter, output, and storage will also be faraway from particular person contraptions and centralized to raise flexibility and reduce the instruments' cost, measurement, and vigor. instruments can also confer with each and every different inside a patient-area community, which will make them less susceptible to scientific error.

    The challenges to integrating Bluetooth in scientific contraptions are mentioned in greater aspect below, however they're the same as for any RF know-how utilized in drugs. Bluetooth has the capabilities of being an adopted and controlled trade general with an intensive qualification, verification, and approval technique to be sure compliance with that specification.

    Implementation. When a tool manufacturer decides to contain Bluetooth into its medical product, it ought to proceed thoughtfully. possibly the easiest way to get began is through the use of an exterior adapter to prototype the equipment design, profit a more advantageous understanding of issues associated with the implementation, and bring together useful person and advertising and marketing feedback. This method could additionally shorten time to market.

    When the prototype is up and operating and a brand is able to navigate the make-versus-purchase selections, it will deserve to believe a number of considerations as it formulates its product and project plans.

    The $5 answer. there was tons discussion in the media about the so-called $5 Bluetooth solution, and a few organizations claim to have finished this greenback quantity per unit for high-extent shipments in 2002.

    The industry intention of $5 contains only the RF and baseband signal processing functions. To put into effect the comprehensive Bluetooth performance from the baseboard layers to profiles and software requires external components (as a minimum an antenna or board space for an onboard implementation, and infrequently other discrete accessories), in addition to RAM, ROM, and processor bandwidth. in addition, all of the latest Bluetooth utility stacks that put into effect more than the headset profile require an operating system.

    The $5 purpose assumes that a device, reminiscent of a cellular phone, already has satisfactory of the above resources and an working equipment. It assumes a royalty-free implementation of the Bluetooth application stack, which is not the case except a device brand implements the rather advanced specification. The aim additionally assumes creation volumes within the tens of millions of units per 12 months.

    sadly, very few of the above circumstances are met for clinical gadgets, so implementations in additional-practical reduce volumes are not likely to satisfy that charge goal. useful estimates for medical gadget functions for the subsequent year latitude from $25 to $70 and would require gigantic building substances. options requiring little or no construction can charge extra however yield brief time to market and can be the most advantageous alternative for low-quantity creation runs, or except client acceptance justifies highly integrated solutions.

    RF add-ons AND issues

    Most medical gadget manufacturers have extensive event, constantly terrible, with RF. traditionally, a great amount of each time and funds are spent attempting to in the reduction of RF emissions and susceptibility. Bluetooth know-how transmits and receives RF alerts, which require rather a unique skill set.


    happily, many wonderful designs are available for Bluetooth that consist of all of the RF components, as a result eliminating this a part of the design assignment. The most desirable Bluetooth RF transceiver will feature poorly, despite the fact, if the design and site of the antenna are omitted. The antenna needs to be located in or on the device to restrict RF shadowing outdoor shielded situations and components. It also has to be designed with the appropriate gain and radiation pattern for a selected application and its placement within the device. usual 2.4-GHz antennas can be found from a number of suppliers and offer many options for placement, sample, benefit, and physical mounting. Board-mount versions are available if the enclosure is radio-transparent and the radiation pattern is applicable for the application. it's important to be aware that plastic fabric choice can make a change for embedded antennas considering that these materials fluctuate of their transparency at 2.4 GHz.

    utility assist for Host Stack. Many scientific equipment manufacturers will now not want or be capable of have enough money a particularly integrated solution that eliminates the HCI and merges the baseband and host processing for his or her gadgets. In most instances, designers will use a module that incorporates the baseband and RF, as well as a Bluetooth application stack in their host utility. reckoning on the category and variety of profiles supported (i.e., the amount of performance required), a scientific machine's Bluetooth utility stack would require:

  • 32–64 KB of code space.
  • 16–32 KB of RAM.
  • approximately 5 tens of millions of guidelines per 2nd of processor bandwidth.
  • (These approximations represent an ordinary of several suppliers'standards.)

    RF issues. The three RF questions most generally asked about Bluetooth and medical devices are: How will it affect the human physique? How smartly will it work with different scientific devices and items used within the home and hospital? How neatly will it work with other applied sciences on the ISM band?

    Human physique exposure. a few organizations modify RF exposure tiers, and papers had been written related to RF's consequences on the human physique. many of the studies that have been completed for 802.11b are also applicable to Bluetooth.

    trying out achieved to date suggests no damage from RF ranges utilized in 802.11b and Bluetooth. Most physique-worn or transportable contraptions is often designed as class three Bluetooth contraptions (1 mW), which would have tremendously much less vigour than many of the transmitters proven (at 100 mW) and are even much less prone to have any deleterious outcomes.

    medical equipment interference and sensitivity. The ISM band is enormously backyard the frequency range of naturally occurring organic alerts; for this reason, the talents possibility of interference to that sign is low and would occur from outcomes on the accessories in a particular gadget design. because Bluetooth is a extremely low vigor transmitter, it is not likely to intrude. Most scientific devices, together with implantable devices, ought to be proven for susceptibility in the ISM band.

    Microwave ovens and a few different gadgets that may well be present in medical settings use the ISM frequency band. Microwave ovens have been found to pose no interference problems, and different devices using ISM-frequency radiation are well shielded to prevent interference with different contraptions.

    Coexistence in the ISM band. clinical gadget corporations and regulatory groups, because of their experiences with hospital telemetry techniques, have a heightened sensitivity to the considerations of interference and coexistence. Their concerns are valid since the hospitals they deliver could already have installed wireless LANs, and distinct ISM radios could exist in other environments as well.

    testing carried out with the aid of a few agencies has proven that however efficiency degradation happens on account of interference, the actual-world outcomes of interference are manageable via current functions. greater work is critical by means of the instant trade to dispose of this problem, but to date interference doesn't seem to be a big subject in most models.

    For the long run, the technologies specification corporations (the Bluetooth SIG and the IEEE 802.15) are working towards interoperability solutions that might get rid of the RF considerations completely.


    Three essential regulatory approvals for wireless clinical devices in the united states are these of Bluetooth, FDA, and FCC. Bluetooth approval is new for scientific device manufacturers, and contraptions devoid of wireless add-ons have traditionally been exempt from FCC approvals in most circumstances. The FDA approval procedure is difficult, exceptionally when new technologies are being introduced.

    Bluetooth Qualification. The Bluetooth qualification method is neatly-described in SIG documentation. Bluetooth expertise keeps a strict enforcement coverage. For businesses to gain free license to the highbrow property that the SIG participants have contributed, the items need to flow the acceptable qualification manner earlier than they're sold (see sidebar). once qualified, the product may also then reveal the Bluetooth manufacturer, logos, and labeling.

    The qualification process is meant to assure clients and users a high stage of interoperability between contraptions. it's taken rather significantly and appears to be positive, to decide from a sampling of items that meet the existing version 1.1 specification. (past versions had interoperability problems, that have been addressed in 1.1; producers may still be cautious of items certified to previous specification revisions.)

    The Bluetooth qualification software allows add-ons to be qualified to a number of stages. Hardware and utility add-ons may also be certified so that a device manufacturer can combine them into a device while not having to repeat the portion of the checking out the component has passed. This ability that if a device company integrates a complete certified OEM module into a tool, that brand needn't do any further trying out to be certified for Bluetooth. different combos of qualified accessories have different sets of implications, so it is critical to consider what qualification work may be required when evaluating whether to make or purchase.

    As of this writing, there are 5 recognized Bluetooth qualification bodies in the u.s. and 26 worldwide accountable for reviewing all of the test outcomes and documentation. in addition, there's one recognized Bluetooth qualification check facility within the united states and four international that may do complete trying out and submission. Many compliance trying out residences have or can have the capacity to perform checking out and create packages for submission to these bodies sooner or later.

    FDA. counting on the implementation and use of Bluetooth, there are several strategies to gaining approval from FDA and overseas organizations. Readers should note that these are competencies paths most effective and need to be reviewed and permitted by way of particular person manufacturers' regulatory affairs workforce.

    If Bluetooth instant know-how is delivered to a device as an exterior adapter with no modifications, corresponding to substitute of an present RS-232 cable, and the gadget is permitted for statistics communications capabilities through that port to external gadget, it may be viable to make use of the regulatory approval approach taken via many machine businesses with exterior modems. If there is not any trade in labeling or meant use it may well be low-priced with no trouble to use what is called a "letter to file." The Bluetooth adapter can be regarded a instant modem during this case, assuming that every one different appropriate business approvals and qualifications have been achieved.

    The regulatory company may still be informed that Bluetooth instant technology is part of an in depth industry regular with tightly enforced qualification and compliance checking out it truly is required for list of a product. Documentation from the Bluetooth qualification check facility and Bluetooth qualification body deliver evidence of this compliance verification. The published specification and check strategies documents are tightly managed through Bluetooth SIG Inc., a U.S. organization based for that aim.

    If Bluetooth is included internally within a tool, submission of a 510(okay) utility to FDA is required, notably as a result of software and hardware changes are more likely to be involved. it is inexpensive to count on that such 510(k) submissions were made or can be made within the near future. the important thing, as with any 510(okay) submissions, is to determine predicate devices and technologies to use in the submission.

    instant and telemetry gadgets have been transport for many years in the united states and worldwide. instruments the usage of wireless applied sciences are at the moment being marketed on the instant clinical telemetry equipment band within the united states that makes use of frequency-hopping unfold-spectrum technologies as well as average frequency modulation know-how. potential predicate gadgets the usage of 802.11 frequency hopping technology in the ISM band had been cleared via FDA and are at the moment being marketed and distributed.

    approved and smartly-confirmed accessories which have a great music list as exterior adaptors should be easier to research separately, and convincing regulatory corporations that they are secure and reliable should be much less of a fight. The exterior approach will additionally allow trying out and gathering of clinical and consumer usage statistics to be covered with a submission.

    FCC. FCC checking out and approval are relatively regular prac- tice in the telecommunications industry, but FCC has not regulated scientific gadgets thus far. once Bluetooth is introduced to a tool, however, FCC testing becomes mandatory since the machine becomes an intentional radiator. Bluetooth RF modules had been designed for FCC compliance, which should enable them to pass the acceptable checking out if the modules are effectively built-in into items.

    a possible possibility to FCC compliance for designs the use of pretested components comes from internal programs' emissions that are coupled into the Bluetooth RF and are reradiated by means of the Bluetooth transmitter and antenna. FCC checking out may also be performed via the equal verify residences presently used for IEC emissions and susceptibility checking out for clinical devices.


    Bluetooth wireless expertise poses new questions about which ingredients of the expertise should still be bought and which parts may still be designed in-house. organizations should cautiously weigh the Bluetooth requirements towards the gadget accessories in terms of supplies, including both hardware and software. Bluetooth qualification and FCC rules should be regarded in the assignment plan. The level of in-condominium abilities should still be regarded as smartly.

    it is effortless so as to add up particular person add-ons on a components-cost groundwork and arrive at a low-fee solution, however using such a technique can produce a disastrous effect when the true expenses of engineering and qualification are fully realized. deciding to buy a stronger-priced, highly integrated solution might keep substantial nonrecurring-cost costs and in the reduction of time to market, which offsets the better expense for a whole product generation. manufacturers should still be cautious to be mindful the true building costs and time table, and the way the two can have an effect on salary calculations.

    It is apparent that scientific devices and clinical information administration items will improvement from the merits offered by Bluetooth wireless know-how. And youngsters Bluetooth definitely items new challenges to the scientific machine business, the merits stand to be quite giant in each latest and future use models for clinical items.


    Bray, Jennifer, and Sturman, Charles F. Bluetooth join with out Cables, 2nd ed. Englewood Cliffs, NJ: Prentice-corridor PTR, 2002.

    William E. Saltzstein is president and founding father of Code Blue Communications, a corporation primarily based in Redmond, WA, that has been constructing Bluetooth know-how.

    Copyright ©2002 medical gadget & Diagnostic industry

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